The Lord tells Abram to go from his country, his kindred and his father's house to the land he will show him. He promises to make him a great nation, bless him, make his name great and make him a blessing; he will bless those who bless him, curse the one who curses him, and in him all the families of the earth will be blessed.
Abram obeys at seventy-five years old and leaves Haran with Sarai his wife, Lot his nephew, and the people and possessions they had gathered. They arrive in the land of Canaan and pass through to Shechem, to the oak of Moreh. The Lord appears to him and promises that land to his offspring, and Abram builds an altar there. Then he moves to the hill country east of Bethel, where he builds another altar and calls on the name of the Lord, and continues toward the Negeb.
A severe famine in the land leads Abram to go down to Egypt. Fearing they will kill him because of his wife's beauty, he asks her to say she is his sister. The Egyptians see that she is beautiful and take her to Pharaoh's house, who treats Abram well. But the Lord afflicts Pharaoh and his household with great plagues because of Sarai. Pharaoh rebukes Abram, returns his wife and orders them sent away with everything he had.