Paul begins by addressing masters: they must treat their slaves justly and fairly, knowing that they too have a Master in heaven. Then he asks the Colossians to continue steadfastly in prayer, being watchful in it with thanksgiving, and to pray also for him and his companions, that God may open a door for the word so that he may declare the mystery of Christ, for which he is in prison, and make it clear as he ought.
He urges them to walk in wisdom toward outsiders, making the best use of the time. Their speech must always be gracious, seasoned with salt, so that they may know how to answer each person.
Then he introduces his co-workers. Tychicus, a beloved brother, faithful minister and fellow servant in the Lord, will tell them all about Paul; with him goes Onesimus, a faithful and beloved brother, who is one of them. Aristarchus, his fellow prisoner, greets them, and Mark, the cousin of Barnabas, about whom they have received instructions and whom they are to welcome if he comes, and Jesus who is called Justus, the only ones of the circumcision who are fellow workers for the kingdom of God and have been a comfort to Paul. Epaphras, who is one of them, a servant of Christ, always struggles on their behalf in his prayers that they may stand mature and fully assured in all the will of God, and he works hard for them and for those in Laodicea and Hierapolis. Luke the beloved physician and Demas also greet them.
Paul sends greetings to the brothers at Laodicea and to Nympha and the church in her house. He asks that when the letter has been read among them, it also be read in the church of the Laodiceans and that they read the letter from Laodicea. To Archippus he says to fulfill the ministry he received in the Lord. He ends with a greeting in his own hand, asking them to remember his chains, and with the wish that grace be with them.